
Amira Ahmed Elwazir
Misr International University, EgyptTitle: Effect of Sodium Hypochlorite (NaOCl) for Pretreatment of Early Demineralized Enamel Lesions in Enhancing the Remineralization Capacity of Self-assembling Peptide (In-vitro Study)
Abstract
As time passes by, our knowledge regarding the different ways of oral
remineralization have improved; leading us to a better understanding of the
concepts of biomimetic regeneration and the more recent technologies that goes
on the other side from fluoride-mediated remineralization.
One of the recent remineralizing technologies is the self-assembling
peptide (SAP) which is considered as an ideal enamel regenerative approach. Its
composition has a great effect on calcium ions affinity, grabbing these ions and
depositing them on a de novo needle-shaped hydroxyapatite mesh work leading
to better in-depth penetration remineralization of demineralized lesions.
Its mode of application is to ensure a clean enamel surface, then start the
surface pretreatment by applying sodium hypochlorite (NaOCl), followed by acid
etching with phosphoric acid gel. Pretreating enamel surface with NaOCl prior to
acid etching acts as a deproteinizing agent removing the organic elements and the
acquired salivary pellicle from the surface; this significantly increases enamel’s
surface retention up to 94.47% and enhances penetrative depths.
The application of NaOCl after acid etching during the process of surface
pretreatment has been discussed in literature proving its effect in enhancing the
shear bond strength values, increasing the penetration and retention of adhesive
resins compared to the conventional way of only acid etch the enamel surface,
and affects the surface roughness of enamel surface with the minimum percentage
of surface loss.
Upon all these findings regarding using NaOCl as an enamel surface
pretreatment and SAP remineralization capabilities, it was found thought-
provoking to study the effect of applying NaOCl as a deproteinizing agent after
acid etching of demineralized sound enamel structure with the aim of minimizing
loss of surface enamel, exposure of more reactive enamel, and creation of
porosities that may allow for more rapid uptake of remineralizing solution as
assessed by surface microhardness testing.
Biography
Amira Elwazir graduated from the Faculty of Dentistry, Misr International
University (MIU), Egypt in 2014. Finished my Masters in Dental Surgery from
MIU in 2020 and proudly published my first thesis in 2021. Dedicated dentist
with six years of practical experience with an interest in scientific research
writing.