Virtual Conference
Pharma Conference 2022

Bushra Khalaf Al-Tarawneh

Mutah university, Jordan

Title: Aggressive fibromatosis of the left mesocolon mimicking a gastrointestinal stromal tumour: A case report-


Mesenteric Fibromatosis (MF) is a proliferative fibroblastic lesion of intestinal mesentery. It constitutes 8% of all desmoid tumours, which represent 0.03% of all neoplasm. It is benign histologically, although it could infiltrate locally and recur following excision, however; without the potential to metastasize. It is spontaneous or associated with Familial Adenomatous Polyposis Mutation (FAP) as a part of Gardner's syndrome. This case report discusses the radiological, intraoperative and histopathological findings from a 45-year-old male patient that presented with abdominal pain and a palpable mass in the left hemiabdomen. Histopathological and immunohistochemical examinations of the resected tumor, including positive staining for beta-catenin, confirmed a postoperative diagnosis of desmoid type fibromatosis. Based on its clinical presentation and computed tomography results, this particular case demonstrated how desmoid type fibromatosis of the colon might mimic gastrointestinal stromal tumors (GIST). Due to the varied therapies and follow-up methods used for these lesions, differential diagnosis between desmoid type fibromatosis and GIST is clinically significant.


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