Ezenwa C.MImo state University Owerri, Nigeria
Title: Studies on the efficacy of various antimycotic drugs on emerging and reemerging, superficial, cutaneous and subcutaneous mycotic infections
Introduction: The efficacy of five systemic and topical antifungal medications, Voriconazole, clotrimazol, beclometasone, Itraconazole, and Fluconazole, on dermatomycosis, which affects the superficial layers of the skin, nails, foot, and hair, was tested with 180 patients.
Methods: Included were specimen collection, processing, microscopy, and culture, as well as antifungal susceptibility testing using the E-test method. The Candida species were confirmed and their susceptibility to Voriconazole and Fluconazole was tested using the automated Vitek 2.
Results: The final strain identification indicated 41 dermatophytes (69.49%), 11 non-dermatophytic molds (NDM) (18.64%), and 7 yeasts (11.87%). (candida). Candida was the most prevalent nondermatophyte species found. Trichophyton rubrum was the most prevalent species isolated in Tinea corporis, T. cruris, T. capitis, and T. faciei. When tested with the E strips, all dermatophyte strains showed the greatest vulnerability to beclometasone and clotrimazole (MIC range of 0.04– 0.64), but homogeneous resistance to Fluconazole (i.e. MIC 32 g/ml).
Conclusion: Variation in species distribution was shown to be statistically significant (p = 0.001)
Ezenwa C.M studied Microbiology at Imo state University Owerri, Nigeria. She has B.sc, MSc and Ph.D in medical Bacteriology, entomology parastiology and public health. She is currently a senior lecturer in the faculty of Biological and health sciences. She has passion for her academic career and has many publications in different aspects of microbiology. She is a Google, LinkedIn, Kudos, Academia and Researchgate scholar. She is an eBook master creator genius and with a general knowledge of data analysis using SPSS. She is also a member of PPSN, OWSD, ASM, NSM, and FEMS. She is also one of the founder of healthmicrobiolglobal.com.