Virtual Conference
Pharma Conference 2022

Iva Furunovikj-Dimitrijevski

PZU Pharmacy Ilinden, Republic of North Macedonia

Title: A survey of AFM1 contamination in row cow milk produced in region of Kumanovo


Aflatoxins (AFs) are type of mycotoxins produced by certain Aspergillus species. In the livers of cows, the aflatoxin ?1 (AFB1) ingested with contaminated food is metabolized in carcinogenic aflatoxin ?1 (AFM1) which is then excreted in the milk and poses a serious risk to the health of the consumers. In January of 2019, twenty five (25) samples of milk were collected from local farms in the surrounding area of Kumanovo, Republic of North Macedonia. The samples were  analysed in the Centre for Public Health, Kumanovo. A method MKC EN ISO 14501:2007 for analysis of AFM1 by HPLC with fluorescence detection was applied. This method is selective, precise and applicative. The final analytical result has shown AFM1 below the LOD in any of the analyzed samples. Due to the wellknown fact that AFM1 is toxic, i.e. carcinogenic and the fact that milk is widely used as staple food, continuous development as well as introduction of new, more sensitive methods for detection of AFM1 are required.


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