The main focus of this study was the antimicrobial effect of 2 medicinal plants that belong to the Algerian Mediterranean flora, Glycyrrhiza glabra and Juniperus phoenicea, The phenolic extracts of Glycyrrhiza glabra and Juniperus phoenicea gave respective yields of 56.15% and 47.40% with methanol/water 70% (v/v). A yield of 52.45% and 42.30% was obtained with ethanol/water 70 % (v/v). Total phenolic results showed that in both plants, the hydroethanolic extract was richer than hydroethanolic extract represented by 122.88±6.64 mg Galic Acid equivalent (GAE)/g dm and 120.54±3.35 mg GAE/g ms. The total flavonoids were about 15.48±4.97 and 14.01 ±8.57 mg EQ/g for J. phoenicea and G. glabra, respectively. Antimicrobial activity results showed that hydromethanolic extract of J. phoenicea, G. glabra, and their combination was more active against Staphylococcus aureus ATCC 33862, whereas they were completely inactive against Pseudomonas aeruginosa ATCC 2785, E. coli ATCC 25922, and C. albicans ATCC 10231. MBC and MIC were 80 and 10 mg/ml for J. phoenicea hydromethanolic extract, 20 and 80 mg/ml for G. glabra hydroethanolic extract, and 2.5 and 20 mg/ml for combined extract, respectively. 

Kheira Zerrouki is a researcher a at the university of Mostaganem, Algeria in the field of Biology, nutrition, food and herbal biomolecules. She is a teacher in the department of food Sciences. Still Master ‘s supervision. Already have been a member in project research. Have done many training in the field of biological and chemical analysis national and international laboratories.