Virtual Conference
Pharma Conference 2022

Masarra M. Sakr

Ain Shams University, Egypt

Title: Minneola tangelo essential oil: A weapon against multidrug resistant pathogens

Abstract

The significant rise in antimicrobial-resistant bacterial strains has become an alarming situation urging the search for new compounds with antimicrobial activity. Plants have a wide range of secondary metabolites as well as an excellent safety profile. In this study, the antimicrobial activity of Minneola tangelo leaf and peel essential oils were assessed against clinical isolates of Acinetobacter baumannii, methicillin-resistant Staphylococcus aureus as well as Shigella and Salmonella sp. The isolates were obtained from El-Demerdash hospital, and their resistance profile was studied using the Kirby-Bauer disk diffusion method. Antibiogram analysis proved that the isolates are multidrug-resistant. Clevenger apparatus was used to extract the essential oils from the leaves and peel and their phytochemical profiling was done using GC/MS. The antibacterial activity was done according to CLSI guidelines. Results showed that the leaf essential oil was active against all the tested isolates, unlike the peel essential that showed no activity on all tested strains. Chemical profiling of the leaf essential oil revealed that linolool, cis-?-ocimene, ?-terpinene were the major constituent representing 31.63%, 16.11%, and 14.35% of the total oil composition, respectively. Further studies are still carried out to determine the possibility of using this essential oil to combat infections caused by the tested isolates.

Biography

Masarra M. Sakr has completed her PhD three years ago from Ain Shams University, Egypt. She is a lecturer of Microbiology and Immunology at the faculty of Pharmacy, Ain Shams University. She has 6 publications, and her h-index is 4.